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Edition/Revision: 1.0
Validated 1 Aug 2001
Validated 1 Aug 2001
Sufentanil
Sufentanil is a synthetic opioid very similar to fentanyl, but with more rapid onset and shorter duration of action.[1] It can be used as an alternative to alfentanil if the fentanyl dose necessitates too large a volume for the portable syringe driver in use. It has also been used sublingually.[2] The clinically derived sufentanil to fentanyl relative potency is approximately 20:1[3]
References
- Scholz J, Steinfath M, Schulz M. Clinical pharmacokinetics of alfentanil, fentanyl and sufentanil. An update. (review) Clin Pharmacokinet 1996;31(4):275-92 [abstract] [full text subs]
- Kunz KM, Theisen JA, Schroeder ME. Severe episodic pain: management with sublingual sufentanil. (letter) J Pain Symptom Manage 1993;8(4):189-90 [more]
- Paix A, Coleman A, Lees J, et al. Subcutaneous fentanyl and sufentanil infusion substitution for morphine intolerance in cancer pain management. Pain 1995;63(2):263-9 [abstract] [full text subs]
Edition/Revision: 1.0
Created 1 Aug 2001
Validated 1 Aug 2001 by Ian Back
Validated 1 Aug 2001 by Ian Back
